Current management and future challenges in salivary glands cancer

Current and future challenges in anaemia management.

The introduction of recombinant human erythropoietin (rhEPO; epoetin) nearly 20 years ago revolutionized the management of renal anaemia. The correction of anaemia with epoetin is associated with improvements in the quality of life of patients with chronic kidney disease (CKD), and reductions in morbidity and mortality. In this supplement, the authors present an overview of pertinent issues in ...

Down Syndrome: Current Status, Challenges and Future Perspectives

Down syndrome (DS) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. It is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. Although the syndrome had been described thousands of years before, it was named after John Langdon Down who described ...

Pancreatic Cancer: Current Progress and Future Challenges.

Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, remains one of the highly lethal malignancies. The highly refractory nature of clinically advanced disease and lack of a reliable biomarker for early detection are major obstructions in improving patient outcome. The recent efforts, however, in understanding the pancreatic tumor biology have resulted in the reco...

Challenges in IPF diagnosis, current management and future perspectives.

Recent developments have clarified our understanding of IPF and improved outcomes with two viable new therapeutic options, pirfenidone and nintedanib. In spite of these advances, questions and challenges concerning IPF still remain. Here we will focus on some of these unresolved areas: the diagnosis of IPF is hindered by limitations in current practice guidelines, surgical lung biopsy is contra...

Subacute Sclerosing Panencephalitis, immunological findings in saliva and salivary glands